Search results for "Salvia multicaulis"

showing 3 items of 3 documents

Chemical composition and phytotoxic effects of essential oils of Salvia hierosolymitana Boiss. and Salvia multicaulis Vahl. var. simplicifolia Boiss.…

2009

The chemical composition of the essential oils of S. hierosolymitana Boiss. and S. multicaulis Vahl. var. simplicifolia Boiss. collected in Lebanon was studied by means of GC and GC-MS analysis. In all 115 compounds were identified: 82 for S hierosolymitana and 72 for S. multicaulis var. simplicifolia. The presence of carbonylic compounds (17%) characterizes the oil from S. hierosolymitana, while S. multicaulis var. simplicifolia oil is rich of monoterpenes (34.5%) and sesquiterpenes (46.9%). The effects of the essential oils on germination and initial radical elongation of Raphanus sativus L. (radish) and Lepidium sativum L. (garden cress) were studied, indicating in a different activity a…

Chromatography GasPharmaceutical ScienceRaphanusBiologyLepidiumSalvia hierosolymitanaArticleGas Chromatography-Mass Spectrometryessential oilAnalytical Chemistrylaw.inventionRaphanuslcsh:QD241-441Salvia hierosolymitana Boiss.lcsh:Organic chemistrylawDrug DiscoveryBotanyRadicleOils VolatilePlant OilsSalviaPhysical and Theoretical ChemistryLebanonEssential oilOrganic Chemistry<i>Salvia hierosolymitana </i>Boiss.; <i>Salvia multicaulis </i>Vahl. var. <i>simplicifolia </i>Boiss.; essential oil; germination; radical elongationbiology.organism_classificationLepidium sativumradical elongationgerminationChemistry (miscellaneous)GerminationSalvia multicaulis Vahl. var. simplicifolia Boiss.Molecular MedicinePhytotoxicitySalvia multicaulis
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Cytotoxicity of abietane diterpenoids from Salvia multicaulis towards multidrug-resistant cancer cells.

2018

Diterpenoids salvimulticanol (1) and salvimulticaoic acid (2) together with known diterpenoid (3-6) were isolated from Salvia multicaulis. Structures were elucidated by spectroscopic techniques including HRESIMS as well as 1D-, and 2D-NMR. In-vitro cytotoxicity was assayed against human cancer cell lines. As several metabolites exhibited activity against drug-resistance lines, compounds were screened against a panel of human drug-sensitive and multidrug-resistant cancer lines. A proposed biosynthetic pathway for these new diterpenoids (1-2) as well as the cytotoxic structure-activity relationship of all identified compounds were discussed. Compound 1 and 6 showed the most potent cytotoxicit…

Phytochemicals01 natural scienceschemistry.chemical_compoundCell Line TumorDrug DiscoverymedicineCytotoxic T cellHumansSalviaCytotoxicityAbietanePharmacologybiologyMolecular Structure010405 organic chemistryChemistryCancerGeneral MedicinePlant Components Aerialbiology.organism_classificationmedicine.diseaseDrug Resistance Multiple0104 chemical sciencesMultiple drug resistance010404 medicinal & biomolecular chemistryCell cultureDrug Resistance NeoplasmCancer cellAbietanesCancer researchEgyptSalvia multicaulisFitoterapia
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Chemical composition of the essential oil of Salvia multicaulis Vahl. var. simplicifolia Boiss. growing wild in Lebanon

2004

The essential oil of aerial parts of Salvia multicaulis Vahl. var. simplicifolia Boiss. (Lamiaceae) growing wild in Lebanon was obtained by hydrodistillation and was analysed by GC and GC-MS. 67 compounds constituting 95.2% of the oil were identified, the major components being alpha-copaene (8.0%), alpha-pinene (6.6%), myrtenol (5.7%), trans-sabinyl acetate (5.3%).

PineneChromatographybiologyTraditional medicineStereochemistryMonoterpeneOrganic ChemistryGeneral MedicinePharmacognosybiology.organism_classificationBiochemistryGas Chromatography-Mass SpectrometryTerpenoidAnalytical Chemistrylaw.inventionchemistry.chemical_compoundchemistrylawMyrtenolOils VolatileLamiaceaeSalviaLebanonEssential oilSalvia multicaulisJournal of Chromatography A
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